Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 2
2004 2
2005 1
2006 4
2007 2
2008 2
2009 3
2010 5
2011 1
2012 2
2013 5
2014 4
2015 3
2016 1
2018 2
2019 1
2020 2
2021 2
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

36 results

Results by year

Filters applied: . Clear all
Page 1
Correlation between ZBRK1/ZNF350 gene polymorphism and breast cancer.
Wu J, Eni A, Roussuri E, Ma B. Wu J, et al. BMC Med Genomics. 2021 Jan 6;14(1):7. doi: 10.1186/s12920-020-00862-2. BMC Med Genomics. 2021. PMID: 33407485 Free PMC article.
BACKGROUND: This study is to explore the relationship between the ZBRK1/ZNF350 (Zinc finger and BRCA1-interacting protein with KRAB domain-1; also known as zinc-finger protein 350) gene polymorphism and early-onset breast cancer. METHODS: The ZBRK1/ …
BACKGROUND: This study is to explore the relationship between the ZBRK1/ZNF350 (Zinc finger and BRCA1-interacting protein with …
Genetic variants and haplotype analyses of the ZBRK1/ZNF350 gene in high-risk non BRCA1/2 French Canadian breast and ovarian cancer families.
Desjardins S, Belleau P, Labrie Y, Ouellette G, Bessette P, Chiquette J, Laframboise R, Lépine J, Lespérance B, Pichette R, Plante M; INHERIT BRCAs; Durocher F. Desjardins S, et al. Int J Cancer. 2008 Jan 1;122(1):108-16. doi: 10.1002/ijc.23058. Int J Cancer. 2008. PMID: 17764113 Free article.
Our current understanding of breast cancer susceptibility involves mutations in the 2 major genes BRCA1 and BRCA2, found in about 25% of high-risk families, as well as few other low penetrance genes such as ATM and CHEK2. Approximately two-thirds of the multiple cas …
Our current understanding of breast cancer susceptibility involves mutations in the 2 major genes BRCA1 and BRCA2, found in about 25% …
Analysis of ZNF350/ZBRK1 promoter variants and breast cancer susceptibility in non-BRCA1/2 French Canadian breast cancer families.
Plourde KV, Labrie Y, Desjardins S, Belleau P, Ouellette G, Durocher F; INHERIT BRCAs. Plourde KV, et al. J Hum Genet. 2013 Feb;58(2):59-66. doi: 10.1038/jhg.2012.127. Epub 2012 Nov 15. J Hum Genet. 2013. PMID: 23151675
ZNF350/ZBRK1 is a transcription factor, which associates with BRCA1 to co-repress GADD45A to regulate DNA damage repair, and the expression of ZNF350 is altered in different human carcinomas. ...This study represents the first characterization step of the …
ZNF350/ZBRK1 is a transcription factor, which associates with BRCA1 to co-repress GADD45A to regulate DNA damage repair, and t …
Functional Evaluation of ZNF350 Missense Genetic Variants Associated with Breast Cancer Susceptibility.
Zhang N, Lu Y, Liu X, Yu D, Lv Z, Yang M. Zhang N, et al. DNA Cell Biol. 2018 Jun;37(6):543-550. doi: 10.1089/dna.2018.4160. Epub 2018 Apr 13. DNA Cell Biol. 2018. PMID: 29653063
ZNF350, a BRCA1-interacting protein, could mediate BRCA1-induced sequence-specific transcriptional repression of several genes, including GADD45alpha. ...Our results highlight ZNF350 as an important gene in human mammary oncogenesis and ZNF350 m …
ZNF350, a BRCA1-interacting protein, could mediate BRCA1-induced sequence-specific transcriptional repression of several genes …
ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer.
Chen K, Yu G, Gumireddy K, Li A, Yao W, Gao L, Chen S, Hao J, Wang J, Huang Q, Xu H, Ye Z. Chen K, et al. Oncotarget. 2015 Mar 30;6(9):6959-76. doi: 10.18632/oncotarget.3134. Oncotarget. 2015. PMID: 25749518 Free PMC article.
In the present study, we identified ZBRK1 as a novel VHL interacting protein by yeast two-hybrid screening, and found a single ZBRK1-binding site located in the VHL promoter region. Ectopic expression of ZBRK1 increases transcriptional activity of the VHL, wh …
In the present study, we identified ZBRK1 as a novel VHL interacting protein by yeast two-hybrid screening, and found a single ZBR …
PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer.
Yeerken D, Hong R, Wang Y, Gong Y, Liu R, Yang D, Li J, Fan J, Chen J, Zhang W, Zhan Q. Yeerken D, et al. PLoS One. 2020 May 29;15(5):e0233750. doi: 10.1371/journal.pone.0233750. eCollection 2020. PLoS One. 2020. PMID: 32470015 Free PMC article.
Real time PCR was used to measure the mRNA expression levels of genes. Western blot was used to detect protein levels. Chromatin immunoprecipitation was used to verify the bindings between transcription factors and DNA elements. ...Consistently, the repressive effects of B …
Real time PCR was used to measure the mRNA expression levels of genes. Western blot was used to detect protein levels. Chromatin immu …
Loss of ZBRK1 contributes to the increase of KAP1 and promotes KAP1-mediated metastasis and invasion in cervical cancer.
Lin LF, Li CF, Wang WJ, Yang WM, Wang DD, Chang WC, Lee WH, Wang JM. Lin LF, et al. PLoS One. 2013 Aug 22;8(8):e73033. doi: 10.1371/journal.pone.0073033. eCollection 2013. PLoS One. 2013. PMID: 23991171 Free PMC article.
The loss of ZBRK1 results in an increase of KAP1 expression, which enhanced migration and invasion of cervical cancer cells both the in vitro and in vivo. ...Taken together, the current results indicate that a loss of ZBRK1 contributes to the increased expression of …
The loss of ZBRK1 results in an increase of KAP1 expression, which enhanced migration and invasion of cervical cancer cells both the …
Mutational analysis of the BRCA1-interacting genes ZNF350/ZBRK1 and BRIP1/BACH1 among BRCA1 and BRCA2-negative probands from breast-ovarian cancer families and among early-onset breast cancer cases and reference individuals.
Rutter JL, Smith AM, Dávila MR, Sigurdson AJ, Giusti RM, Pineda MA, Doody MM, Tucker MA, Greene MH, Zhang J, Struewing JP. Rutter JL, et al. Hum Mutat. 2003 Aug;22(2):121-8. doi: 10.1002/humu.10238. Hum Mutat. 2003. PMID: 12872252
Two potential breast cancer susceptibility genes, encoding the BRCA1-interacting proteins ZNF350 (or ZBRK1) and BRIP1 (or BACH1), have been identified in yeast two-hybrid screens. ...Based on sequencing of ZBRK1 and BRIP1 in 21 BRCA1/2-negative proband …
Two potential breast cancer susceptibility genes, encoding the BRCA1-interacting proteins ZNF350 (or ZBRK1) and BRIP1 ( …
The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2.
Hallen L, Klein H, Stoschek C, Wehrmeyer S, Nonhoff U, Ralser M, Wilde J, Röhr C, Schweiger MR, Zatloukal K, Vingron M, Lehrach H, Konthur Z, Krobitsch S. Hallen L, et al. Hum Mol Genet. 2011 Jan 1;20(1):104-14. doi: 10.1093/hmg/ddq436. Epub 2010 Oct 6. Hum Mol Genet. 2011. PMID: 20926453
Here, we report the identification of the KRAB-containing zinc-finger transcriptional regulator, ZBRK1, as an interaction partner of the SCA2 gene product ataxin-2. Furthermore, we discovered that an elevated ZBRK1 level resulted in increased ataxin-2 levels, …
Here, we report the identification of the KRAB-containing zinc-finger transcriptional regulator, ZBRK1, as an interaction partner of …
High-density array analysis of DNA methylation in Tamoxifen-resistant breast cancer cell lines.
Williams KE, Anderton DL, Lee MP, Pentecost BT, Arcaro KF. Williams KE, et al. Epigenetics. 2014 Feb;9(2):297-307. doi: 10.4161/epi.27111. Epub 2013 Nov 13. Epigenetics. 2014. PMID: 24225485 Free PMC article.
Aberrant DNA methylation, an epigenetic mechanism that alters gene expression in cancer, is thought to play a role in this resistance. ...Analysis of CpG sites altered in both TMX2-11 and TMX2-28 revealed that the Tamoxifen-resistant cell lines share 3000 hypermethylated a …
Aberrant DNA methylation, an epigenetic mechanism that alters gene expression in cancer, is thought to play a role in this resistance …
36 results